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Dr. Singh and Lee Gerdes' most recent paper, Overcoming Depression through Brain State Conditioning, was published in the Frontiers in Neurosciene Magazine (Vol. 3, Issue 2).
Depression or major depressive disorder (MDD) is a very serious medical illness affecting an estimated 25 million Americans and millions more worldwide. It significantly changes an individuals ability to function on a daily basis. Symptoms include persistently sad or irritable mood, pronounced changes in sleep, appetite, and energy, difficulty thinking, concentrating, and remembering, physical slowing or agitation, lack of interest in, or pleasure from, activities that were once enjoyed, feelings of guilt, worthlessness, hopelessness, and emptiness, recurrent thoughts of death or suicide and persistent physical symptoms that do not respond to treatment, such as headaches, digestive disorders, and chronic pain. The cause of depression is not very well understood, but the disorder has a neurobiological basis (Mayberg, 2007). We hypothesized that depressed individuals have an imbalance in the brain (Gerdes, 2008) and conducted a pilot study of brain training using brain state conditioning (BSC). We found that depressive tendencies can be suppressed by BSC.
Download the entire article here.

Vijendra K. Singh, Ph.D, is the Director of Neuroscience Research at the Brain State Technologies in Scottsdale, Arizona. After graduating from Lucknow University, India, he received his doctorate from the University of British Columbia, Vancouver, Canada. Formerly a Professor at the University of Michigan, Utah State University, Medical University of South Carolina and University of British Columbia. He has devoted his entire career to studying brain diseases, mental illnesses and immune deficiency disorders. Currently he leads research into brain training modalities, including BSC, to help people who suffer from brain diseases and mental health problems. vsingh@brainstatetech.com
Lee Gerdes is CEO of Brain State Technologies, LLC, Scottsdale, AZ, a company with 140 affiliate offices in 18 countries. Lees education includes a B.A. in Math and Physics, Doane College, Crete, Nebraska; Master of Divinity, Wartburg Seminary, Dubuque, IA; graduate work in engineering at Columbia University, New York; and graduate work in Clinical Psychology, JFK University, Orinda, CA. Lee has 40 years of experience in the computer software field and has previously served as VP of Solutions for Net Perceptions and as Principal Consultant and software applications design leader for other companies and consulting firms. leeg@brainstatetech.com

Beck, A. T. (1996). Becks Anxiety Inventory (BAI) and Becks Depression Inventory, 2nd Edition (BDI-II), The Psychological Corporation, Harcourt Brace & Company, San Antonio, Texas, USA.
Gerdes, L. (2008). Limitless You: the infinite possibilities of a balanced brain. (Vancouver BC., Canada, Namaste Publishing ), pp. 1-281.
MacMaster, F. P., Mirza, Y., and Szeszko, P. R. (2008). Amygdala and hippocampal volumes in familial onset major depressive disorder. Biol. Psychiatr. 63, 385-390.
Mayberg, H. (2007). Brain pathway may underlie depression. Sci. Am. 17, 26-31.
Sen, S., Duman, R., and Sanacora, G. (2008). Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analysis and implications. Biol. Psychiatr. 64, 527-532.